# Molecular Manufacturing Copies Evolution's Bottom-up Construction by Ed Regis > “The idea sounds fatuous in the extreme…until you remember that objects as big and complex as whales, dinosaurs, and sumo wrestlers got built in a moderately analogous fashion: they began as minute, nanoscale structures that duplicated themselves, and whose successors then differentiated off into specialized organs and other components. Those growing ranks of biological marvels did all this repeatedly until, eventually, they had automatically assembled themselves into complex and functional macroscale entities. And the initial seed structures, the gametes, were not even designed, built, or programmed by scientists: they were just out there in the world, products of natural selection. But if nature can do that all by itself, then why can't machines be intelligently engineered to accomplish relevantly similar feats?” > **— Ed Regis**, *2009, Edge Annual Question, “What Will Change Everything?”* ## Sources and Context - **Direct Edge response and surrounding essay:** [MOLECULAR MANUFACTURING](https://www.edge.org/response-detail/10165) — Edge published this exact passage in its 2009 Annual Question collection, *WHAT WILL CHANGE EVERYTHING?*. The response page preserves the surrounding argument and qualifications. - **Complete local collection index:** [[research/Edge 2009 Full Quotation Curation|Edge 2009 Full Quotation Curation]] — retained source-first record for the complete response cohort and this passage's promotion status. ## Related Articles and Collections - **Collection:** [[collections/Edge|Edge]] - **Collection:** [[collections/Machine Succession|Machine Succession]] - **Article:** [[articles/The Evolutionary Roots of Silicon Valley|Valley Roots]] - **Article:** [[articles/Digital Darwinism and the Invisible World of Machine Evolution|Digital Darwinism]] - **Article:** [[articles/We Were Never Going to Make It|Never Going to Make It!]] - **Wiki map:** [[wiki/Evolutionary Biology|Evolutionary Biology]] ## Related Topics - [[wiki/Evolutionary Biology|Evolutionary Biology]] - [[wiki/Unit of Selection|Unit of Selection]] - [[wiki/Selection Gradient|Selection Gradient]] - [[wiki/Evolvability|Evolvability]] ## Share on Social Media ``` “The idea sounds fatuous in the extreme…until you remember that objects as big and complex as whales, dinosaurs, and sumo wrestlers got built in a moderately analogous fashion: they began as minute, nanoscale structures that duplicated themselves, and whose successors then differentiated off into specialized organs and other components. Those growing ranks of biological marvels did all this repeatedly until, eventually, they had automatically assembled themselves into complex and functional macroscale entities. And the initial seed structures, the gametes, were not even designed, built, or programmed by scientists: they were just out there in the world, products of natural selection. But if nature can do that all by itself, then why can't machines be intelligently engineered to accomplish relevantly similar feats?” — Ed Regis, 2009, Edge Annual Question, “What Will Change Everything?” https://bryantmcgill.com/simple-reminders-ed-regis-molecular-manufacturing-copies-evolution-s ```