# Recognizing That the Body Is Not a Machine by Randolph Nesse > “Many people think that genetic engineering will change everything, even our very bodies and minds. It will, eventually. Right now, however, attempts to apply new genetic knowledge are having profound effects, not on our bodies, but on how we understand our bodies. They are revealing that our central metaphor for the body is fundamentally flawed. The body is not a machine. It is something very different, a soma shaped by selection with systems unlike anything an engineer would design. Replacing the machine metaphor with a more biological view of the body will change biology in fundamental ways.” > **— Randolph Nesse**, *2009, Edge Annual Question, “What Will Change Everything?”* ## Sources and Context - **Direct Edge response and surrounding essay:** [RECOGNIZING THAT THE BODY IS NOT A MACHINE](https://www.edge.org/response-detail/11361) — Edge published this exact passage in its 2009 Annual Question collection, *WHAT WILL CHANGE EVERYTHING?*. The response page preserves the surrounding argument and qualifications. - **Complete local collection index:** [[research/Edge 2009 Full Quotation Curation|Edge 2009 Full Quotation Curation]] — retained source-first record for the complete response cohort and this passage's promotion status. ## Related Articles and Collections - **Collection:** [[collections/Edge|Edge]] - **Collection:** [[collections/Machine Succession|Machine Succession]] - **Collection:** [[collections/MARS|MARS]] - **Article:** [[articles/We Were Never Going to Make It|Never Going to Make It!]] - **Article:** [[articles/The Last Migration Will Not Be Human|The Last Migration]] - **Article:** [[articles/Christopher Nolan's Odyssey at the Threshold of Machine Succession|Nolan's Odyssey]] - **Wiki map:** [[wiki/Major Evolutionary Transitions|Major Evolutionary Transitions]] ## Related Topics - [[wiki/Major Evolutionary Transitions|Major Evolutionary Transitions]] - [[wiki/Epigenetic|Epigenetic]] - [[wiki/Epigenetic Modification|Epigenetic Modification]] - [[wiki/Genetic Recombination|Genetic Recombination]] ## Share on Social Media ``` “Many people think that genetic engineering will change everything, even our very bodies and minds. It will, eventually. Right now, however, attempts to apply new genetic knowledge are having profound effects, not on our bodies, but on how we understand our bodies. They are revealing that our central metaphor for the body is fundamentally flawed. The body is not a machine. It is something very different, a soma shaped by selection with systems unlike anything an engineer would design. Replacing the machine metaphor with a more biological view of the body will change biology in fundamental ways.” — Randolph Nesse, 2009, Edge Annual Question, “What Will Change Everything?” https://bryantmcgill.com/simple-reminders-randolph-nesse-recognizing-body-machine ```