# Life Evolves via a Shared Genetic Toolkit by Seirian Sumner > “Genes and their interaction networks determine the phenotype of an organism—what it looks like and how it behaves. One of the biggest problems in modern evolutionary biology is understanding the relationship between genes and phenotypes. The prevailing theory is that all animals are built from essentially the same set of regulatory genes—a genetic toolkit, and that phenotypic variation within and between species arises simply by using shared genes differently. Scientists are now generating a vast amount of genomic data from an eclectic mix of organisms. These data are telling us to put to bed the idea that all life is underlain by a common toolkit of conserved genes. Instead, we need to turn our attention to the role of genomic novelty in the evolution of phenotypic diversity and innovation.” > **— Seirian Sumner**, *2014, Edge Annual Question, “What Scientific Idea Is Ready For Retirement?”* ## Sources and Context - **Direct Edge response and surrounding essay:** [Life Evolves Via A Shared Genetic Toolkit](https://www.edge.org/response-detail/25533) — Edge published this exact passage in its 2014 Annual Question collection, *WHAT SCIENTIFIC IDEA IS READY FOR RETIREMENT?*. The response page preserves the surrounding argument and qualifications. - **Complete local collection index:** [[research/Edge 2014 Full Quotation Curation|Edge 2014 Full Quotation Curation]] — retained source-first record for the complete response cohort and this passage's promotion status. ## Related Articles and Collections - **Collection:** [[collections/Edge|Edge]] - **Collection:** [[collections/Machine Succession|Machine Succession]] - **Article:** [[articles/The Evolutionary Roots of Silicon Valley|Valley Roots]] - **Article:** [[articles/Digital Darwinism and the Invisible World of Machine Evolution|Digital Darwinism]] - **Article:** [[articles/We Were Never Going to Make It|Never Going to Make It!]] - **Wiki map:** [[wiki/Evolutionary Biology|Evolutionary Biology]] ## Related Topics - [[wiki/Evolutionary Biology|Evolutionary Biology]] - [[wiki/Epigenetic Modification|Epigenetic Modification]] - [[wiki/Genetic Recombination|Genetic Recombination]] - [[wiki/Evolutionary Covariation|Evolutionary Covariation]] ## Share on Social Media ``` “Genes and their interaction networks determine the phenotype of an organism—what it looks like and how it behaves. One of the biggest problems in modern evolutionary biology is understanding the relationship between genes and phenotypes. The prevailing theory is that all animals are built from essentially the same set of regulatory genes—a genetic toolkit, and that phenotypic variation within and between species arises simply by using shared genes differently. Scientists are now generating a vast amount of genomic data from an eclectic mix of organisms. These data are telling us to put to bed the idea that all life is underlain by a common toolkit of conserved genes. Instead, we need to turn our attention to the role of genomic novelty in the evolution of phenotypic diversity and innovation.” — Seirian Sumner, 2014, Edge Annual Question, “What Scientific Idea Is Ready For Retirement?” https://bryantmcgill.com/simple-reminders-seirian-sumner-life-evolves-via-shared-genetic ```