# Connectome **Entity class:** Concept or analytic term **Collection:** [[collections/Neurotech|Neurotech]] **Type:** Neuroanatomical graph concept **Primary sources:** [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]]; [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] ## Definition A **connectome** is a map of neural elements and their connections at a declared scale and resolution. Nodes may represent neurons or regions; edges may represent synapses, projections, or inferred connectivity. ## Relationships - [[wiki/Structural Connectomics|Structural connectomics]] produces connectomes from anatomy. - [[wiki/Functional Connectomics|Functional connectomics]] co-registers wiring with measured activity. - [[wiki/FlyWire|FlyWire]], [[wiki/H01 Connectome|H01]], and [[wiki/MICrONS|MICrONS]] instantiate different species, scale, and modality choices. - A connectome is not automatically an executable model or a sufficient record of identity. <!-- BEGIN HUMANIZED RELATIONSHIPS 2026-09-11 --> This entry's documented connections are expressed in its definition and related-work routes, with provenance retained in the source-linked material. <!-- END HUMANIZED RELATIONSHIPS 2026-09-11 --> ## Related Work in the Corpus <!-- BEGIN HUMANIZED CORPUS ROUTES 2026-09-11 --> - In [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]], **Connectomics: The Upstream Reference Infrastructure** provides the narrative context for **Connectome**: The critical epistemic shift enabling next-generation BCI decoding is that connectomics has transitioned from producing static 'maps' to generating reference address spaces—versioned, tooled, continuously improving infrastructure… - In [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]], **FlyWire: Whole-Brain Completeness at Insect Scale** provides the narrative context for **Connectome**: The FlyWire Consortium, co-led by Mala Murthy (Director of the Princeton Neuroscience Institute and Karol and Marnie Marcin '96 Professor of Neuroscience) and Sebastian Seung (Evnin Professor in Neuroscience and Professor of… - In [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]], **MICrONS: Function-Structure Registration at Mammalian Scale** provides the narrative context for **Connectome**: The MICrONS (Machine Intelligence from Cortical Networks) program—funded by IARPA (Intelligence Advanced Research Projects Activity) and NIH—achieved the critical mammalian-scale bridge with its April 2025 Nature collection… <!-- END HUMANIZED CORPUS ROUTES 2026-09-11 -->