Electron Microscopy - Bryant McGill

# Electron Microscopy **Entity class:** Concept or analytic term **Collection:** [[collections/Neurotech|Neurotech]] **Aliases:** EM **Type:** Imaging method **Primary sources:** [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]]; [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] ## Definition **Electron microscopy** uses electron beams rather than visible light to image material at nanometer scales. In connectomics, serial tissue sections are imaged and computationally assembled into large three-dimensional volumes. ## Relationships - [[wiki/Davi Bock|Davi Bock]] led the EM imaging underlying [[wiki/FlyWire|FlyWire]]. - EM volumes supply input to [[wiki/Neuronal Segmentation|neuronal segmentation]] and [[wiki/Connectome Proofreading|proofreading]]. - [[wiki/MICrONS|MICrONS]] co-registers EM structure with [[wiki/Calcium Imaging|calcium imaging]]. - [[wiki/LICONN|LICONN]] is a light-microscopy alternative described within the reconstruction stack.  This entry is routed through [[collections/Neurotech|Neurotech]]. Its source context is developed in [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]], [[articles/Mind Uploading and AI — The Host is Reusable and the Person is the Delta|Mind Uploading and AI — The Host is Reusable and the Person is the Delta]], [[articles/Technologies for Consciousness Mapping and Transfer|Technologies for Consciousness Mapping and Transfer]], and [[articles/The Architecture of Continuity and Emerging Neuroinformatics Standards|The Architecture of Continuity and Emerging Neuroinformatics Standards]]. Status-qualified source edges are preserved in the terminal Research Edges section. ### Additional Documented Relationships - [[wiki/MICrONS|MICrONS]] is associated with **Electron Microscopy**. Function-structure registration.  ## Related Work in the Corpus  - In [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]], **FlyWire: Whole-Brain Completeness at Insect Scale** provides the narrative context for **Electron Microscopy**: The FlyWire Consortium, co-led by Mala Murthy (Director of the Princeton Neuroscience Institute and Karol and Marnie Marcin '96 Professor of Neuroscience) and Sebastian Seung (Evnin Professor in Neuroscience and Professor of… - In [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]], **MICrONS: Function-Structure Registration at Mammalian Scale** provides the narrative context for **Electron Microscopy**: The MICrONS (Machine Intelligence from Cortical Networks) program—funded by IARPA (Intelligence Advanced Research Projects Activity) and NIH—achieved the critical mammalian-scale bridge with its April 2025 Nature collection…  ## Research Edges  #### Master relationship graph patch — 2026-09-10 **Collection:** [[collections/Neurotech|Neurotech]] **Relationship source:** [[research/Neurotechnology Ecosystem Relationship Graph - 2026-09-10|Neurotechnology Ecosystem Relationship Graph — 2026-09-10]] **Related source articles:** [[articles/The Architecture of Continuity and Emerging Neuroinformatics Standards|The Architecture of Continuity and Emerging Neuroinformatics Standards]] · [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]] · [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] #### Incoming typed edges - **Edge 347 — [[wiki/MICrONS|MICrONS]] `integrates` → this entry** — **CORPUS**; evidence `CORPUS_ATLAS`, `MICRONS_ALLEN`. Function-structure registration.