# Electron Microscopy **Collection:** [[collections/Neurotech|Neurotech]] **Aliases:** EM **Type:** Imaging method **Primary sources:** [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]]; [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] ## Definition **Electron microscopy** uses electron beams rather than visible light to image material at nanometer scales. In connectomics, serial tissue sections are imaged and computationally assembled into large three-dimensional volumes. ## Relationships - [[wiki/Davi Bock|Davi Bock]] led the EM imaging underlying [[wiki/FlyWire|FlyWire]]. - EM volumes supply input to [[wiki/Neuronal Segmentation|neuronal segmentation]] and [[wiki/Connectome Proofreading|proofreading]]. - [[wiki/MICrONS|MICrONS]] co-registers EM structure with [[wiki/Calcium Imaging|calcium imaging]]. - [[wiki/LICONN|LICONN]] is a light-microscopy alternative described within the reconstruction stack. <!-- BEGIN NEUROTECH RELATIONSHIP GRAPH 2026-09-10 --> ### Master relationship graph patch — 2026-09-10 **Collection:** [[collections/Neurotech|Neurotech]] **Relationship source:** [[research/Neurotechnology Ecosystem Relationship Graph - 2026-09-10|Neurotechnology Ecosystem Relationship Graph — 2026-09-10]] **Related source articles:** [[articles/The Architecture of Continuity and Emerging Neuroinformatics Standards|The Architecture of Continuity and Emerging Neuroinformatics Standards]] · [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]] · [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] #### Incoming typed edges - **Edge 347 — [[wiki/MICrONS|MICrONS]] `integrates` → this entry** — **CORPUS**; evidence `CORPUS_ATLAS`, `MICRONS_ALLEN`. Function-structure registration. #### Epistemic boundary `VERIFIED`, `VERIFIED_SECONDARY`, `CORPUS`, `STRONG_TECHNICAL_LINEAGE`, `STRONG_TECHNICAL_CONVERGENCE`, `ANALYTIC`, and `UNRESOLVED` are retained as distinct relation states. An edge does not imply ownership, control, funding, licensing, technology transfer, or organizational identity unless its predicate and evidence state that relationship explicitly. <!-- END NEUROTECH RELATIONSHIP GRAPH 2026-09-10 -->