# FlyWire **Domain:** Connectomics / Neuroinformatics **Doc Type:** Dataset and Consortium Node **Maturity:** Published Research Infrastructure **Primary Source:** [[articles/The Art is Long|The Art is Long: Vespucci of Immortality]] **Related:** [[wiki/Connectomics|Connectomics]], [[wiki/Effectome|Effectome]], [[wiki/MICrONS|MICrONS]], [[wiki/State Sufficiency Problem|State Sufficiency Problem]] --- ## Definition **FlyWire** is a collaborative connectomics project that produced a complete synapse-resolution wiring diagram of the adult fruit-fly brain and made the reconstruction browsable as shared research infrastructure. ## Continuity Significance Connectome-constrained models built from the fly visual system produced neuron-level activity predictions that could be tested against measurements. The result marks a transition from a wiring diagram as static map to structure as a constraint on executable function. ## Evidentiary Boundary The connectome specifies possible paths of influence. It does not by itself preserve causal strength, sign, gain, neuromodulation, short-term plasticity, or the full living state of the animal. ## Sources / Provenance - [Neuronal wiring diagram of an adult brain](https://www.nature.com/articles/s41586-024-07558-y).