# Genome > **Machine-Evolution Nexus:** [[articles/Digital Darwinism and the Invisible World of Machine Evolution|Digital Darwinism and the Invisible World of Machine Evolution]] places this concept within the history and governance of substrate-independent evolution. **Domain:** Genetics / Digital Evolution **Doc Type:** Canonical Wiki Node **Maturity:** Developed ## Definition A genome is the inherited informational organization of an organism or digital evolutionary individual. ## Machine-Evolution Context Biological genomes are nucleic-acid systems embedded in cells; Avida and Tierra use executable instruction sequences as digital genomes. The shared term identifies a hereditary role, not material sameness. ## Continuity and Evidence Boundary A genome is neither a complete organism nor a complete person. Expression depends on machinery, history and environment. ## Relationships [[wiki/Genotype|Genotype]], [[wiki/Heritable Information|Heritable Information]], [[wiki/Digital Organism|Digital Organism]], [[wiki/Operational Substrate|Operational Substrate]] ## Sources / Provenance - Modern genetics; Avida and Tierra literature.