# Genome Engineering **Entity class:** Biotechnology **Domain:** Artificial intelligence / science / political economy **Maturity:** Developed ## Definition **Genome Engineering** is the deliberate reading, modification, or construction of genetic instructions in living systems. ## Mechanism and Consequence AI expands the searchable design space and can make candidate interventions easier to generate, but biological verification, delivery, off-target effects, inheritance, and governance remain material constraints. ## Relationships - [[wiki/Biotechnology|Biotechnology]] - [[wiki/AI-Driven Biology|AI-Driven Biology]] - [[wiki/AI Control|AI Control]] - [[wiki/Scientific Literacy|Scientific Literacy]] ## Source Dossiers - [[research/AI Is Now So Good They Will Pay You to Quit|AI Is Now So Good They Will Pay You to Quit]] - [[research/Super Intelligence Week Index of Statements from the White House Luncheon|Super Intelligence Week Index of Statements from the White House Luncheon]] - [[research/Jensen Pushes Back on Doomers Moonshots Live|Jensen Pushes Back on Doomers Moonshots Live]] ## Simple Reminders, Quotations, and Thoughts > "As genome editing merges with what may become possible through AI, the possible benefits go through the roof, and the possible downsides go through the roof as well. We are now in full Frankenstein mode, so there is ammunition here for the AI-doom argument." > **— Salim Ismail**, *MOONSHOTS Live, September 25, 2026* [[reminders/Biotechnology/AI Genome Editing Raises Benefits and Dangers Together by Salim Ismail|AI Genome Editing Raises Benefits and Dangers Together by Salim Ismail]] > "Once we discovered CRISPR, we learned that we could edit the human genome as easily as a Word document or software. When you learn a new language, you learn reading, then comprehension, then writing. We have now learned how to write to the genome. Each human body has roughly fifty trillion cells governed by what DNA tells those cells to do, which means a human being has become a software-engineering problem." > **— Salim Ismail**, *MOONSHOTS Live, September 25, 2026* [[reminders/Biotechnology/Humanity Has Become a Software-Engineering Problem by Salim Ismail|Humanity Has Become a Software-Engineering Problem by Salim Ismail]]