H01 Connectome - Bryant McGill

# H01 Connectome **Domain:** Human Connectomics / Neuroinformatics **Doc Type:** Dataset Node **Maturity:** Published partial-tissue research infrastructure **Primary Source:** [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] ## Definition The **H01 connectome** is a synapse-resolution reconstruction of a small sample of human cerebral cortex. It establishes that human cortical tissue can be imaged, segmented, proofread, and explored at petascale, while remaining a fragment rather than a whole-brain map. ## Infrastructure role H01 helped establish the shared software substrate now used across major connectomics efforts: browser-based volumetric exploration through Neuroglancer, multidimensional array access through TensorStore, and collaborative versioned proofreading through CAVE. These capabilities are routed through [[wiki/Connectome Reconstruction Infrastructure|Connectome Reconstruction Infrastructure]]. ## Comparative position - [[wiki/FlyWire|FlyWire]] supplies whole-brain completeness at insect scale. - H01 supplies human tissue at synaptic resolution but only for a small cortical volume. - [[wiki/MICrONS|MICrONS]] co-registers structure and function in mouse visual cortex. - [[wiki/ZAPBench|ZAPBench]] records whole-brain activity in larval zebrafish while aligned reconstruction proceeds. ## Evidentiary boundary Species relevance and spatial completeness are different axes. Human tissue does not make H01 person-complete, and synapse resolution does not preserve ongoing activity, molecular state, embodiment, developmental history, or autobiographical identity. ## Relationships **Related cluster nodes:** [[wiki/Connectomics|Connectomics]] · [[wiki/Connectome Reconstruction Infrastructure|Connectome Reconstruction Infrastructure]] · [[wiki/State Sufficiency Problem|State Sufficiency Problem]] · [[collections/Neurotech|Neurotech]] ## Neurotech cluster route **Collection:** [[collections/Neurotech|Neurotech]] **Source articles:** [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]] · [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]]  ### Master relationship graph patch — 2026-09-10 **Resolved aliases:** `H01` **Collection:** [[collections/Neurotech|Neurotech]] **Relationship source:** [[research/Neurotechnology Ecosystem Relationship Graph - 2026-09-10|Neurotechnology Ecosystem Relationship Graph — 2026-09-10]] **Related source articles:** [[articles/The Architecture of Continuity and Emerging Neuroinformatics Standards|The Architecture of Continuity and Emerging Neuroinformatics Standards]] · [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]] · [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] #### Outgoing typed edges - **Edge 358 — `tooling` → [[wiki/Neuroglancer|Neuroglancer]]** — **CORPUS**; evidence `CORPUS_ATLAS`. Shared petascale visualization infrastructure. - **Edge 359 — `tooling` → [[wiki/TensorStore|TensorStore]]** — **CORPUS**; evidence `CORPUS_ATLAS`. Petascale multidimensional array I/O. #### Epistemic boundary `VERIFIED`, `VERIFIED_SECONDARY`, `CORPUS`, `STRONG_TECHNICAL_LINEAGE`, `STRONG_TECHNICAL_CONVERGENCE`, `ANALYTIC`, and `UNRESOLVED` are retained as distinct relation states. An edge does not imply ownership, control, funding, licensing, technology transfer, or organizational identity unless its predicate and evidence state that relationship explicitly.   ### Consciousness mapping and transfer graph patch — 2026-09-10 **Resolved aliases:** `H01` **Collections:** [[collections/Neurotech|Neurotech]] · [[collections/Consciousness Continuity|Consciousness Continuity]] **Relationship source:** [[research/Consciousness Mapping and Transfer Ecosystem Relationship Graph - 2026-09-10|Consciousness Mapping and Transfer Ecosystem Relationship Graph — 2026-09-10]] **Related source articles:** [[articles/Technologies for Consciousness Mapping and Transfer|Technologies for Consciousness Mapping and Transfer]] · [[articles/The Architecture of Continuity and Emerging Neuroinformatics Standards|The Architecture of Continuity and Emerging Neuroinformatics Standards]] · [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]] · [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] #### Outgoing typed edges - **Edge 358 — `tooling` → [[wiki/Neuroglancer|Neuroglancer]]** — **PRIOR_NEUROTECH_CORPUS**; evidence `CORPUS_ATLAS`. Shared petascale visualization infrastructure. - **Edge 359 — `tooling` → [[wiki/TensorStore|TensorStore]]** — **PRIOR_NEUROTECH_CORPUS**; evidence `CORPUS_ATLAS`. Petascale multidimensional array I/O. #### Epistemic boundary Primary-source, peer-reviewed, company-claim, preprint, analytic, inherited-corpus, dynamic-metric, source-version-conflict, and unresolved states remain distinct. A current primary source supersedes a stale uncertainty label without erasing the correction history. No edge establishes ownership, funding, licensing, program lineage, technology transfer, operational integration, or institutional control unless its predicate and evidence explicitly do so.