# Kathleen G. C. Leeper **Aliases:** Kathleen Leeper **Entity class:** Molecular-barcoding researcher **Collection:** [[collections/Neurotech|Neurotech]] **Canonical source articles:** [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] · [[articles/Technologies for Consciousness Mapping and Transfer|Technologies for Consciousness Mapping and Transfer]] ## Definition **Kathleen G. C. Leeper** is an E11 Bio co-founder and lead scientist for barcoding. Before E11 she worked in [[wiki/George Church|George Church]]'s group on spatial transcriptomics, super-resolution microscopy, cell engineering, and CRISPR-enabled lineage tracing, and later helped establish [[wiki/Reza Kalhor|Reza Kalhor]]'s laboratory work on genomic recording and genome mapping. This trajectory forms a documented laboratory lineage into PRISM's protein-barcoding architecture. The PRISM contribution statement credits Leeper with conceptualization; design, cloning, and testing of the C-terminal eGFP barcode system; barcode characterization; volume registration; and writing. She is also named on the related patent application. ## Relationships - **Organization:** [[wiki/E11 Bio|E11 Bio]]. - **Laboratory lineage:** [[wiki/George Church|George Church]] and [[wiki/Reza Kalhor|Reza Kalhor]]. - **Direct contribution:** [[wiki/PRISM (E11 Bio)|PRISM (E11 Bio)]] protein barcodes. - **Patent inventorship:** [[wiki/WO2025106572A1|WO2025106572A1]]. - **Collection route:** [[collections/Neurotech|Neurotech]]. ## Sources - [E11 Bio — Kathleen Leeper](https://www.e11.bio/kathleen-leeper) - [PubMed Central — PRISM author contributions](https://pmc.ncbi.nlm.nih.gov/articles/PMC12485930/)