# LICONN **Collection:** [[collections/Neurotech|Neurotech]] **Expansion:** Light-microscopy-based Connectomics **Type:** Connectomic imaging and reconstruction method **Primary source:** [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] ## Relationships - LICONN combines hydrogel expansion, conventional light microscopy, molecular labeling, and learned segmentation to reconstruct synapse-level tissue. - It was developed through the Institute of Science and Technology Austria and Google Research relationship described in the atlas. - It belongs to [[wiki/Connectome Reconstruction Infrastructure|Connectome Reconstruction Infrastructure]] and contributes to [[wiki/Multimodal Connectomics|multimodal connectomics]]. LICONN's accessibility advantage over electron microscopy does not erase limits in tissue volume, labeling, reconstruction confidence, or cross-method comparability. <!-- BEGIN NEUROTECH RELATIONSHIP GRAPH 2026-09-10 --> ### Master relationship graph patch — 2026-09-10 **Collection:** [[collections/Neurotech|Neurotech]] **Relationship source:** [[research/Neurotechnology Ecosystem Relationship Graph - 2026-09-10|Neurotechnology Ecosystem Relationship Graph — 2026-09-10]] **Related source articles:** [[articles/The Architecture of Continuity and Emerging Neuroinformatics Standards|The Architecture of Continuity and Emerging Neuroinformatics Standards]] · [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]] · [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] #### Incoming typed edges - **Edge 364 — [[wiki/Connectomics|connectomics]] `tooling` → this entry** — **CORPUS**; evidence `CORPUS_ATLAS`. Reconstruction infrastructure. #### Epistemic boundary `VERIFIED`, `VERIFIED_SECONDARY`, `CORPUS`, `STRONG_TECHNICAL_LINEAGE`, `STRONG_TECHNICAL_CONVERGENCE`, `ANALYTIC`, and `UNRESOLVED` are retained as distinct relation states. An edge does not imply ownership, control, funding, licensing, technology transfer, or organizational identity unless its predicate and evidence state that relationship explicitly. <!-- END NEUROTECH RELATIONSHIP GRAPH 2026-09-10 --> <!-- BEGIN CONSCIOUSNESS MAPPING TRANSFER RELATIONSHIP GRAPH 2026-09-10 --> ### Consciousness mapping and transfer graph patch — 2026-09-10 **Collections:** [[collections/Neurotech|Neurotech]] · [[collections/Consciousness Continuity|Consciousness Continuity]] **Relationship source:** [[research/Consciousness Mapping and Transfer Ecosystem Relationship Graph - 2026-09-10|Consciousness Mapping and Transfer Ecosystem Relationship Graph — 2026-09-10]] **Related source articles:** [[articles/Technologies for Consciousness Mapping and Transfer|Technologies for Consciousness Mapping and Transfer]] · [[articles/The Architecture of Continuity and Emerging Neuroinformatics Standards|The Architecture of Continuity and Emerging Neuroinformatics Standards]] · [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]] · [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] #### Incoming typed edges - **Edge 364 — [[wiki/Connectomics|connectomics]] `tooling` → this entry** — **PRIOR_NEUROTECH_CORPUS**; evidence `CORPUS_ATLAS`. Reconstruction infrastructure. #### Epistemic boundary Primary-source, peer-reviewed, company-claim, preprint, analytic, inherited-corpus, dynamic-metric, source-version-conflict, and unresolved states remain distinct. A current primary source supersedes a stale uncertainty label without erasing the correction history. No edge establishes ownership, funding, licensing, program lineage, technology transfer, operational integration, or institutional control unless its predicate and evidence explicitly do so. <!-- END CONSCIOUSNESS MAPPING TRANSFER RELATIONSHIP GRAPH 2026-09-10 -->