# MERFISH **Expanded name:** Multiplexed Error-Robust Fluorescence In Situ Hybridization **Entity class:** Spatial transcriptomics method **Collections:** [[collections/Neurotech|Neurotech]] · [[collections/Consciousness Continuity|Consciousness Continuity]] ## Definition **MERFISH** is a highly multiplexed imaging method for measuring RNA molecules while retaining their spatial organization in tissue. ## Relationships - MERFISH contributes molecular and spatial cell-state evidence to [[wiki/BICAN|BICAN]]-class atlas work. - It complements [[wiki/Patch-seq|Patch-seq]], [[wiki/BARseq|BARseq]], and [[wiki/Connectomics|connectomics]] without making their measurements interchangeable. - The method is routed from [[articles/Technologies for Consciousness Mapping and Transfer|Technologies for Consciousness Mapping and Transfer]] as part of the molecular-state layer. <!-- BEGIN HUMANIZED RELATIONSHIPS 2026-09-11 --> This entry's documented connections are expressed in its definition and related-work routes, with provenance retained in the source-linked material. <!-- END HUMANIZED RELATIONSHIPS 2026-09-11 --> ## Related Work in the Corpus <!-- BEGIN HUMANIZED CORPUS ROUTES 2026-09-11 --> - In [[articles/Technologies for Consciousness Mapping and Transfer|Technologies for Consciousness Mapping and Transfer]], **IV. The brain as [[wiki/Connectomic Reference Address Space|address space]]** provides the narrative context for **MERFISH**: The connectome is also becoming typed. <!-- END HUMANIZED CORPUS ROUTES 2026-09-11 -->