# Machine Learning Segmentation
**Collection:** [[collections/Neurotech|Neurotech]]
**Type:** Computational imaging method
**Primary sources:** [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]]; [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]]
## Definition
**Machine-learning segmentation** uses trained models to identify and separate structures in image data. Connectomics applies it to dense microscopy volumes where manual tracing alone would be prohibitive.
## Relationships
- Flood-filling networks and PATHFINDER are routed through [[wiki/Connectome Reconstruction Infrastructure|Connectome Reconstruction Infrastructure]].
- [[wiki/FlyWire Consortium|FlyWire]] combined automated segmentation with 33 reported person-years of proofreading.
- Model output remains a provisional reconstruction until error detection, review, and provenance controls are applied.