# MouseLight **Entity class:** Whole-brain single-neuron reconstruction project **Collection:** [[collections/Neurotech|Neurotech]] **Canonical source articles:** [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] · [[articles/Technologies for Consciousness Mapping and Transfer|Technologies for Consciousness Mapping and Transfer]] ## Definition **MouseLight** is a Janelia project that images whole mouse brains at submicron resolution and reconstructs complete axonal arbors of individual neurons. Its 2019 release reported more than 1,000 reconstructed projection neurons and made the data available through an interactive browser. MouseLight supplies a long-range morphology and registration lineage for [[wiki/Johan Winnubst|Johan Winnubst]], who later developed PRISM's stitching and registration pipeline. Sparse whole-neuron reconstruction and PRISM's molecularly annotated optical reconstruction are related but distinct methods. ## Relationships - **Institution:** [[wiki/Janelia Research Campus|Janelia Research Campus]]. - **Principal-scientist lineage:** [[wiki/Johan Winnubst|Johan Winnubst]]. - **Technical ancestry of:** [[wiki/PRISM (E11 Bio)|PRISM (E11 Bio)]] stitching, registration, and long-range morphology work. - **Collection route:** [[collections/Neurotech|Neurotech]]. ## Sources - [Janelia — MouseLight](https://www.janelia.org/project-team/mouselight) - [Janelia — MouseLight maps 1,000 neurons](https://www.janelia.org/news/mouselight-project-team-maps-1000-neurons-and-counting-in-the-mouse-brain)