# Multimodal Connectomics **Collection:** [[collections/Neurotech|Neurotech]] **Type:** Integrated neuroscience method **Primary sources:** [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]]; [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] ## Definition **Multimodal connectomics** combines connectivity with additional modalities such as activity, cell type, molecular markers, gene expression, or morphology in a registered coordinate system. ## Relationships - [[wiki/MICrONS|MICrONS]] combines electron-microscopy structure and calcium-imaging function. - LICONN adds molecular labeling to light-microscopy reconstruction through [[wiki/Connectome Reconstruction Infrastructure|reconstruction infrastructure]]. - Registration and provenance determine whether modalities describe the same tissue, individual, region, and time point.