# Nanometer-Resolution Imaging **Entity class:** Concept or analytic term **Collection:** [[collections/Neurotech|Neurotech]] **Type:** Imaging-resolution concept **Primary source:** [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]] ## Definition **Nanometer-resolution imaging** resolves structures at billionths-of-a-meter scale, enabling synapses, fine neurites, and cellular boundaries to be distinguished in connectomic tissue volumes. ## Relationships - [[wiki/Electron Microscopy|Electron microscopy]] is the principal modality in the FlyWire source passage. - The images become input to [[wiki/Machine Learning Segmentation|machine-learning segmentation]] and human [[wiki/Connectome Proofreading|connectome proofreading]]. - Resolution is one attribute; volume coverage, contrast, tissue preparation, and reconstruction accuracy remain separate. <!-- BEGIN HUMANIZED RELATIONSHIPS 2026-09-11 --> This entry's documented connections are expressed in its definition and related-work routes, with provenance retained in the source-linked material. <!-- END HUMANIZED RELATIONSHIPS 2026-09-11 --> ## Related Work in the Corpus <!-- BEGIN HUMANIZED CORPUS ROUTES 2026-09-11 --> - In [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]], **FlyWire: Whole-Brain Completeness at Insect Scale** provides the narrative context for **Nanometer-Resolution Imaging**: The FlyWire Consortium, co-led by Mala Murthy (Director of the Princeton Neuroscience Institute and Karol and Marnie Marcin '96 Professor of Neuroscience) and Sebastian Seung (Evnin Professor in Neuroscience and Professor of… <!-- END HUMANIZED CORPUS ROUTES 2026-09-11 -->