Precision Neuroscience - Bryant McGill

# Precision Neuroscience **Entity class:** Concept or analytic term **Domain:** Cortical-Surface Brain-Computer Interfaces / Clinical Neurotechnology **Doc Type:** Company and Platform Node **Maturity:** Clinical research and regulatory translation **Primary Source:** [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] ## Definition **Precision Neuroscience** develops the **Layer 7 Cortical Interface**, a high-density, thin-film electrode array designed to conform to the cortical surface. The approach seeks higher spatial resolution than non-invasive systems without penetrating neural tissue with individual electrode shanks or threads. ## Architectural position The Layer 7 design occupies the surface-array region between endovascular and penetrating interfaces. The source atlas emphasizes three linked properties: high electrode density, placement through a narrow surgical opening, and reversibility through removal of the surface film. Its comparative value is architectural. [[wiki/Synchron|Synchron]] accepts lower-dimensional vascular recording to reduce surgical burden; [[wiki/Neuralink|Neuralink]] and [[wiki/Paradromics|Paradromics]] penetrate cortex for bandwidth; [[wiki/Blackrock Neurotech|Blackrock Neurotech]] supplies the long-running implanted reference architecture. Precision Neuroscience tests whether conforming surface access can retain useful bandwidth while reducing tissue penetration. ## Evidentiary boundary Temporary intraoperative testing, an announced regulatory filing, and permanent commercial implantation are different milestones. Reversibility of the array's placement does not eliminate surgical, data-governance, or long-term biocompatibility questions. ## Relationships **Related cluster nodes:** [[collections/Neurotech|Neurotech]] · [[wiki/Brain-Computer Interfaces|Brain-Computer Interfaces]] · [[wiki/Electrocorticography|Electrocorticography]] · [[wiki/Invasive BCI|Invasive BCI]] · [[wiki/Biocompatibility|Biocompatibility]]  This entry is routed through [[collections/Neurotech|Neurotech]] and [[collections/Consciousness Continuity|Consciousness Continuity]]. Its source context is developed in [[articles/Technologies for Consciousness Mapping and Transfer|Technologies for Consciousness Mapping and Transfer]], [[articles/The Architecture of Continuity and Emerging Neuroinformatics Standards|The Architecture of Continuity and Emerging Neuroinformatics Standards]], [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]], and [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]]. Status-qualified source edges are preserved in the terminal Research Edges section. ### People and institutional relationships - **Precision Neuroscience** was co-founded by [[wiki/Benjamin Rapoport|Benjamin Rapoport]]. - **Precision Neuroscience** was co-founded by [[wiki/Michael Mager|Michael Mager]]. - **Precision Neuroscience** employs [[wiki/Craig Mermel|Craig Mermel]]. Chief AI and Data Officer. ### Technology and research relationships - **Precision Neuroscience** develops [[wiki/Layer 7 Cortical Interface|Layer 7 Cortical Interface]]. High-density surface array; FDA 510(k) clearance for limited-duration cortical interface is reported by company. ### Key Relationships - **Precision Neuroscience** has as a clinical partner [[wiki/Mount Sinai|Mount Sinai]]. One of many current clinical partners; source lists 15+. - **Precision Neuroscience** has as a clinical partner [[wiki/Mass General Brigham|Mass General Brigham]]. - **Precision Neuroscience** has as a clinical partner [[wiki/Michigan Medicine|Michigan Medicine]]. ### Additional Documented Relationships - The source corpus interprets the relationship this way: [[wiki/Less-Invasive Brain-Computer Interface|Less-Invasive Brain-Computer Interface]] is bridged through **Precision Neuroscience**. Different access geometries solving common surgery/bandwidth trade-space.  ## Related Work in the Corpus  - In [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]], **Movement VII — Interface Deployment: The Neurointerface Stack from Wearable to Implanted** provides the narrative context for **Precision Neuroscience**: Wiki route: brain-computer interfaces · non-invasive BCI · invasive BCI · Neuralink · Synchron · Precision Neuroscience · Blackrock Neurotech · Paradromics · BCI HID.  ## Research Edges  #### Master relationship graph patch — 2026-09-10 **Collection:** [[collections/Neurotech|Neurotech]] **Relationship source:** [[research/Neurotechnology Ecosystem Relationship Graph - 2026-09-10|Neurotechnology Ecosystem Relationship Graph — 2026-09-10]] **Related source articles:** [[articles/The Architecture of Continuity and Emerging Neuroinformatics Standards|The Architecture of Continuity and Emerging Neuroinformatics Standards]] · [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]] · [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] #### Outgoing typed edges - **Edge 281 — `co_founded_by` → [[wiki/Benjamin Rapoport|Benjamin Rapoport]]** — **VERIFIED**; evidence `PRECISION_VISION`. - **Edge 283 — `co_founded_by` → [[wiki/Michael Mager|Michael Mager]]** — **VERIFIED**; evidence `PRECISION_VISION`. - **Edge 284 — `develops` → [[wiki/Layer 7 Cortical Interface|Layer 7 Cortical Interface]]** — **VERIFIED**; evidence `PRECISION_HOME`, `PRECISION_VISION`. High-density surface array; FDA 510(k) clearance for limited-duration cortical interface is reported by company. - **Edge 285 — `employs` → [[wiki/Craig Mermel|Craig Mermel]]** — **VERIFIED**; evidence `PRECISION_VISION`. Chief AI and Data Officer. - **Edge 288 — `clinical_partner` → [[wiki/Mount Sinai|Mount Sinai]]** — **VERIFIED**; evidence `PRECISION_HOME`. One of many current clinical partners; source lists 15+. - **Edge 289 — `clinical_partner` → [[wiki/Mass General Brigham|Mass General Brigham]]** — **VERIFIED**; evidence `PRECISION_HOME`. - **Edge 290 — `clinical_partner` → [[wiki/Michigan Medicine|Michigan Medicine]]** — **VERIFIED**; evidence `PRECISION_HOME`. #### Incoming typed edges - **Edge 410 — [[wiki/Less-Invasive Brain-Computer Interface|less-invasive BCI]] `bridge_entities` → this entry** — **ANALYTIC**; evidence `SYNCHRON_TECH`, `SUB_TECH`, `MERGE_OPENAI`, `PRECISION_VISION`. Different access geometries solving common surgery/bandwidth trade-space.   #### Consciousness mapping and transfer graph patch — 2026-09-10 **Collections:** [[collections/Neurotech|Neurotech]] · [[collections/Consciousness Continuity|Consciousness Continuity]] **Relationship source:** [[research/Consciousness Mapping and Transfer Ecosystem Relationship Graph - 2026-09-10|Consciousness Mapping and Transfer Ecosystem Relationship Graph — 2026-09-10]] **Related source articles:** [[articles/Technologies for Consciousness Mapping and Transfer|Technologies for Consciousness Mapping and Transfer]] · [[articles/The Architecture of Continuity and Emerging Neuroinformatics Standards|The Architecture of Continuity and Emerging Neuroinformatics Standards]] · [[articles/2026 Annual Report on Brain-Computer Interfaces|2026 Annual Report on Brain-Computer Interfaces]] · [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] #### Outgoing typed edges - **Edge 281 — `co_founded_by` → [[wiki/Benjamin Rapoport|Benjamin Rapoport]]** — **PRIOR_NEUROTECH_VERIFIED**; evidence `PRECISION_VISION`. - **Edge 283 — `co_founded_by` → [[wiki/Michael Mager|Michael Mager]]** — **PRIOR_NEUROTECH_VERIFIED**; evidence `PRECISION_VISION`. - **Edge 284 — `develops` → [[wiki/Layer 7 Cortical Interface|Layer 7 Cortical Interface]]** — **PRIOR_NEUROTECH_VERIFIED**; evidence `PRECISION_HOME`, `PRECISION_VISION`. High-density surface array; FDA 510(k) clearance for limited-duration cortical interface is reported by company. - **Edge 285 — `employs` → [[wiki/Craig Mermel|Craig Mermel]]** — **PRIOR_NEUROTECH_VERIFIED**; evidence `PRECISION_VISION`. Chief AI and Data Officer. - **Edge 288 — `clinical_partner` → [[wiki/Mount Sinai|Mount Sinai]]** — **PRIOR_NEUROTECH_VERIFIED**; evidence `PRECISION_HOME`. One of many current clinical partners; source lists 15+. - **Edge 289 — `clinical_partner` → [[wiki/Mass General Brigham|Mass General Brigham]]** — **PRIOR_NEUROTECH_VERIFIED**; evidence `PRECISION_HOME`. - **Edge 290 — `clinical_partner` → [[wiki/Michigan Medicine|Michigan Medicine]]** — **PRIOR_NEUROTECH_VERIFIED**; evidence `PRECISION_HOME`.  ## Research Inferences  These entries translate the forward-looking register in [[research/Research Inferences|Research Inferences]] into ordinary wiki prose. The tier labels apply to the inference, not automatically to every factual anchor inside it. The interpretive frame comes from [[articles/Technologies for Consciousness Mapping and Transfer|Technologies for Consciousness Mapping and Transfer]] and [[articles/Mind Uploading and AI — The Host is Reusable and the Person is the Delta|Mind Uploading and AI — The Host is Reusable and the Person is the Delta]]. Collection route: [[collections/Neurotech|Neurotech]]. - **INF-0005 — Plausible.** Thin-film surface arrays trade single-unit resolution for reversibility and coverage area. Reversibility is the property that makes iteration possible: a device that can be removed can be upgraded, and upgradeability is what turns an implant from a terminal procedure into a subscription substrate.