# RNA Editing **Domain:** Molecular Biology / Neuroscience **Doc Type:** Scientific Concept Node **Maturity:** Established **Related:** [[U3 Molecular Data Classes]], [[Proteostasis]], [[Long-Term Memory Substrate]] --- ## Definition **RNA editing** changes RNA sequence information after transcription, potentially altering the proteins or regulatory behavior produced from a genomic template. In neural systems, RNA editing and splice variation can affect receptors, ion channels, signaling, and cellular state. ## Continuity relevance Genomic sequence alone may not specify the active molecular configuration of a neuron. A high-fidelity state model may need transcriptomic and editing context in addition to anatomy and connectivity.