# Whole Mouse Brain Connectome **Entity class:** Concept or analytic term **Type:** Connectomics objective **Collection:** [[collections/Neurotech|Neurotech]] **Primary source:** [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] ## Definition Whole Mouse Brain Connectome is a connectomics objective identified in the source article's the mammalian-scale structural mapping objective beyond MICrONS layer. ## Relationships [[wiki/Whole Mouse Brain Connectome|Whole Mouse Brain Connectome]] is related to [[wiki/Whole-Brain Connectomics|Whole-Brain Connectomics]] as the mammalian-scale structural mapping objective beyond MICrONS. <!-- BEGIN HUMANIZED RELATIONSHIPS 2026-09-11 --> This entry's documented connections are expressed in its definition and related-work routes, with provenance retained in the source-linked material. <!-- END HUMANIZED RELATIONSHIPS 2026-09-11 --> ## Source route [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]] · [[collections/Neurotech|Neurotech]] ## Related Work in the Corpus <!-- BEGIN HUMANIZED CORPUS ROUTES 2026-09-11 --> - In [[articles/The Organic-Synthetic Brain Atlas|The Organic-Synthetic Brain Atlas]], **III.6 — The Mouse Brain Effort and the Path to Whole-Mammalian Connectomics** provides the narrative context for **Whole Mouse Brain Connectome**: The current frontier of connectomic ambition is the whole mouse brain connectome. <!-- END HUMANIZED CORPUS ROUTES 2026-09-11 --> ## Research Inferences <!-- BEGIN RESEARCH INFERENCES 2026-09-11 --> These entries translate the forward-looking register in [[research/Research Inferences|Research Inferences]] into ordinary wiki prose. The tier labels apply to the inference, not automatically to every factual anchor inside it. The interpretive frame comes from [[articles/Technologies for Consciousness Mapping and Transfer|Technologies for Consciousness Mapping and Transfer]] and [[articles/Mind Uploading and AI — The Host is Reusable and the Person is the Delta|Mind Uploading and AI — The Host is Reusable and the Person is the Delta]]. Collection route: [[collections/Neurotech|Neurotech]]. - **INF-0111 — Strongly indicated.** At current electron-microscopy economics a whole mouse brain implies tens of billions of dollars; at a 100× reduction it becomes a large-instrument-scale project comparable to a telescope. That crossing converts the mouse connectome from a thought experiment into a fundable program. <!-- END RESEARCH INFERENCES 2026-09-11 --> ## Simple Reminders, Quotations, and Thoughts <!-- BEGIN SIMPLE REMINDER SEED 2026-09-11 --> > "We anticipate PRISM will be essential for scaling up whole-brain connectomics from small brains, to the large brains of mice and ultimately humans — a critical need for making more human-like AI, treating brain disorders, and even simulating our own brain circuitry." > **— Andrew C. Payne**, *2024, E11 Bio connectomics roadmap* [[reminders/Connectomics/Toward Simulating Our Own Brain Circuitry by Andrew C. Payne|Toward Simulating Our Own Brain Circuitry by Andrew C. Payne]] <!-- END SIMPLE REMINDER SEED 2026-09-11 -->